MAG monoclonal antibody (M35), clone 3C7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant MAG.
Immunogen
MAG (NP_002352, 119 a.a. ~ 208 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
GDLGGYNQYTFSEHSVLDIVNTPNIVVPPEVVAGTEVEVSCMVPDNCPELRPELSWLGHEGLGEPAVLGRLREDEGTWVQVSLLHFVPTR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (99); Rat (98)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
MAG monoclonal antibody (M35), clone 3C7. Western Blot analysis of MAG expression in Jurkat(Cat # L017V1 ).Western Blot (Recombinant protein)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to MAG on formalin-fixed paraffin-embedded human cerebellum. [antibody concentration 3 ug/ml]Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged MAG is 0.1 ng/ml as a capture antibody.ELISA
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Gene Info — MAG
Entrez GeneID
4099GeneBank Accession#
NM_002361Protein Accession#
NP_002352Gene Name
MAG
Gene Alias
GMA, S-MAG, SIGLEC-4A, SIGLEC4A
Gene Description
myelin associated glycoprotein
Omim ID
159460Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq
Other Designations
myelin-associated glycoprotein|sialic acid-binding immunoglobulin-like lectin 4A
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Interactome
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Pathway
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Disease
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