SMAD6 (Human) Recombinant Protein (Q01)

Catalog # H00004091-Q01

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Size:25 ug
Price: USD $ 510.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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QC Test

  • Specification

    Product Description

    Human SMAD6 partial ORF (NP_005576, 285 a.a. - 384 a.a.) recombinant protein with GST-tag at N-terminal.

    Sequence

    RDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTR

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    36.74

    Interspecies Antigen Sequence

    Mouse (99)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — SMAD6

    Entrez GeneID

    4091

    GeneBank Accession#

    NM_005585

    Protein Accession#

    NP_005576

    Gene Name

    SMAD6

    Gene Alias

    HsT17432, MADH6, MADH7

    Gene Description

    SMAD family member 6

    Omim ID

    602931

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants encoding different isoforms have been found for this gene

    Other Designations

    MAD (mothers against decapentaplegic, Drosophila) homolog 6|MAD, mothers against decapentaplegic homolog 6|Mothers against decapentaplegic, drosophila, homolog of, 6|SMAD, mothers against DPP homolog 6

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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