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NBR1 rabbit monoclonal antibody

  • Catalog # : H00004077-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human NBR1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human NBR1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human NBR1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 4077
  • GeneBank Accession#:
  • NBR1
  • Gene Name:
  • NBR1
  • Gene Alias:
  • 1A1-3B,KIAA0049,M17S2,MIG19
  • Gene Description:
  • neighbor of BRCA1 gene 1
  • Gene Summary:
  • The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled coil motif, which is present in many genes with transformation potential, but the function of this protein is unknown. This gene is located on a region of chromosome 17q21.1 that is in close proximity to tumor suppressor gene BRCA1. Three alternatively spliced variants encoding the same protein have been identified for this gene. [provided by RefSeq
  • Other Designations:
  • membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125),migration-inducing protein 19
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