M6PR (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human M6PR partial ORF ( NP_002346, 211 a.a. - 277 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
33.11
Interspecies Antigen Sequence
Mouse (100); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — M6PR
Entrez GeneID
4074GeneBank Accession#
NM_002355Protein Accession#
NP_002346Gene Name
M6PR
Gene Alias
CD-MPR, FLJ32994, MPR46, SMPR
Gene Description
mannose-6-phosphate receptor (cation dependent)
Omim ID
154540Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane. [provided by RefSeq
Other Designations
46-kDa mannose 6-phosphate receptor|Mr 46,000 Man6PR|cation-dependent mannose-6-phosphate receptor
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Interactome
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