M6PR polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (33.48 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant M6PR.
Immunogen
M6PR (NP_002346, 211 a.a. ~ 277 a.a) partial recombinant protein with GST tag.
Sequence
QRLVVGAKGMEQFPHLAFWQDLGNLVADGCDFVCRSKPRNVPAAYRGVGDDQLGEESEERDDHLLPM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (99)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (33.48 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — M6PR
Entrez GeneID
4074GeneBank Accession#
NM_002355Protein Accession#
NP_002346Gene Name
M6PR
Gene Alias
CD-MPR, FLJ32994, MPR46, SMPR
Gene Description
mannose-6-phosphate receptor (cation dependent)
Omim ID
154540Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for mannose-6-phosphate groups on lysosomal enzymes. The receptor forms a homodimer or homotetramer for intracellular targeting of lysosomal enzymes and export of newly synthesized lysosomal enzymes into the cell secretions. The receptor is an integral membrane protein which localizes to the trans-Golgi reticulum, endosomes, and the plasma membrane. [provided by RefSeq
Other Designations
46-kDa mannose 6-phosphate receptor|Mr 46,000 Man6PR|cation-dependent mannose-6-phosphate receptor
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Interactome
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Pathway
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Disease
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Publication Reference
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Pitchfork Regulates Primary Cilia Disassembly and Left-Right Asymmetry.
Kinzel D, Boldt K, Davis EE, Burtscher I, Trumbach D, Diplas B, Attie-Bitach T, Wurst W, Katsanis N, Ueffing M, Lickert H.
Developmental Cell 2010 Jul; 19(1):66.
Application：IF, Mouse, Primary limb cultures.
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HGF-induced invasion by prostate tumor cells requires anterograde lysosome trafficking and activity of Na+-H+ exchangers.
Steffan JJ, Williams BC, Welbourne T, Cardelli JA.
Journal of Cell Science 2010 Apr; 123(Pt 7):1151.
Application：IF, Human, DU145 cells.
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Pitchfork Regulates Primary Cilia Disassembly and Left-Right Asymmetry.
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