LTBR monoclonal antibody (M08), clone 8C7
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LTBR.
Immunogen
LTBR (NP_002333.1, 37 a.a. ~ 225 a.a) partial recombinant protein.
Sequence
ASENQTCRDQEKEYYEPQHRICCSRCPPGTYVSAKCSRIRDTVCATCAENSYNEHWNYLTICQLCRPCDPVMGLEEIAPCTSKRKTQCRCQPGMFCAAWALECTHCELLSDCPPGTEAELKDEVGKGNNHCVPCKAGHFQNTSSPSARCQPHTRCENQGLVEAAPGTAQSDTTCKNPLEPLPPEMSGTM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (71); Rat (67)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — LTBR
Entrez GeneID
4055GeneBank Accession#
NM_002342.1Protein Accession#
NP_002333.1Gene Name
LTBR
Gene Alias
D12S370, LT-BETA-R, TNF-R-III, TNFCR, TNFR-RP, TNFR2-RP, TNFRSF3
Gene Description
lymphotoxin beta receptor (TNFR superfamily, member 3)
Omim ID
600979Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the tumor necrosis factor (TNF) family of receptors. It is expressed on the surface of most cell types, including cells of epithelial and myeloid lineages, but not on T and B lymphocytes. The protein specifically binds the lymphotoxin membrane form (a complex of lymphotoxin-alpha and lymphtoxin-beta). The encoded protein and its ligand play a role in the development and organization of lymphoid tissue and tranformed cells. Activation of the encoded protein can trigger apoptosis. [provided by RefSeq
Other Designations
TNFR superfamily, member 3|lymphotoxin B receptor|lymphotoxin beta receptor|tumor necrosis factor C receptor|tumor necrosis factor receptor superfamily, member 3
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Interactome
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Pathway
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Disease
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