LTBP1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human LTBP1 partial ORF ( NP_000618, 403 a.a. - 500 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
CPGGMGYTVSGVHRRRPIHHHVGKGPVFVKPKNTQPVAKSTHPPPLPAKEEPVEALTFSREHGPGVAEPEVATAPPEKEIPSLDQEKTKLEPGQPQLS
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.52
Interspecies Antigen Sequence
Mouse (89); Rat (92)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LTBP1
Entrez GeneID
4052GeneBank Accession#
NM_000627Protein Accession#
NP_000618Gene Name
LTBP1
Gene Alias
MGC163161
Gene Description
latent transforming growth factor beta binding protein 1
Omim ID
150390Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq
Other Designations
TGF-beta1-BP-1
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Interactome
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Pathway
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Disease
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