LSS rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LSS peptide using ARM Technology.
Immunogen
A synthetic peptide of human LSS is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LSS peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LSS
Entrez GeneID
4047GeneBank Accession#
LSSGene Name
LSS
Gene Alias
FLJ25486, FLJ35015, FLJ39450, FLJ46393, OSC
Gene Description
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Omim ID
600909Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms
Other Designations
2,3-epoxysqualene--lanosterol cyclase|lanosterol synthase
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