LRP5 monoclonal antibody (M01), clone 1E9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LRP5.
Immunogen
LRP5 (NP_002326.1, 41 a.a. ~ 130 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
RDVRLVDAGGVKLESTIVVSGLEDAAAVDFQFSKGAVYWTDVSEEAIKQTYLNQTGAAVQNVVISGLVSPDGLACDWVGKKLYWTDSETN
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (97); Rat (97)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged LRP5 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — LRP5
Entrez GeneID
4041GeneBank Accession#
NM_002335Protein Accession#
NP_002326.1Gene Name
LRP5
Gene Alias
BMND1, EVR1, EVR4, HBM, LR3, LRP7, OPPG, OPS, OPTA1, VBCH2
Gene Description
low density lipoprotein receptor-related protein 5
Gene Ontology
HyperlinkOther Designations
exudative vitreoretinopathy 1|low density lipoprotein receptor-related protein 7|osteoporosis pseudoglioma syndrome
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Interactome
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Pathway
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Disease
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Publication Reference
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The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage.
Badders NM, Goel S, Clark RJ, Klos KS, Kim S, Bafico A, Lindvall C, Williams BO, Alexander CM.
PLoS One 2009 Aug; 4(8):e6594.
Application:IF, Flow Cyt, IHC-P, WB, Mouse, Mouse embryo, mammary gland, primary MECs, NMuMG, HC11 cells.
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The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage.
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