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Last updated: 2017/5/21

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LNPEP rabbit monoclonal antibody

  • Catalog # : H00004012-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human LNPEP peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human LNPEP is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human LNPEP peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 4012
  • GeneBank Accession#:
  • LNPEP
  • Gene Name:
  • LNPEP
  • Gene Alias:
  • CAP,IRAP,P-LAP,PLAP
  • Gene Description:
  • leucyl/cystinyl aminopeptidase
  • Gene Summary:
  • This gene encodes a zinc-dependent aminopeptidase that cleaves vasopressin, oxytocin, lys-bradykinin, met-enkephalin, dynorphin A and other peptide hormones. The protein can be secreted in maternal serum, reside in intracellular vesicles with the insulin-responsive glucose transporter GLUT4, or form a type II integral membrane glycoprotein. The protein catalyzes the final step in the conversion of angiotensinogen to angiotensin IV (AT4) and is also a receptor for AT4. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
  • Other Designations:
  • AT (4) receptor,OTTHUMP00000196800,angiotensin IV receptor,insulin-regulated aminopeptidase,insulin-responsive aminopeptidase,otase,oxytocinase,placental leucine aminopeptidase,vasopressinase
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