LMX1A (Human) Recombinant Protein (P01)

Catalog # H00004009-P01

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Size:25 ug
Price: USD $ 510.00
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Size:10 ug
Price: USD $ 335.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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  • Specification

    Product Description

    Human LMX1A full-length ORF ( NP_001028679.1, 1 a.a. - 100 a.a.) recombinant protein with GST-tag at N-terminal.Full-Length Protein,Full-Length Proteins,Full-Length,Full Length,FullLength

    Sequence

    MEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS

    Host

    Wheat Germ (in vitro)

    Theoretical MW (kDa)

    37.4

    Interspecies Antigen Sequence

    Mouse (98); Rat (98)

    Preparation Method

    in vitro wheat germ expression system

    Purification

    Glutathione Sepharose 4 Fast Flow

    Quality Control Testing

    12.5% SDS-PAGE Stained with Coomassie Blue.

    Storage Buffer

    50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

    Storage Instruction

    Store at -80°C. Aliquot to avoid repeated freezing and thawing.

    Note

    Best use within three months from the date of receipt of this protein.

  • Applications

    Enzyme-linked Immunoabsorbent Assay

    Western Blot (Recombinant protein)

    Antibody Production

    Protein Array

  • Gene Info — LMX1A

    Entrez GeneID

    4009

    GeneBank Accession#

    NM_001033507.1

    Protein Accession#

    NP_001028679.1

    Gene Name

    LMX1A

    Gene Alias

    LMX-1, LMX1, LMX1.1, MGC87616

    Gene Description

    LIM homeobox transcription factor 1, alpha

    Omim ID

    600298

    Gene Ontology

    Hyperlink

    Gene Summary

    Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM

    Other Designations

    OTTHUMP00000032530|OTTHUMP00000032531|OTTHUMP00000032532

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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