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Last updated: 2016/10/23

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LMX1A rabbit monoclonal antibody

  • Catalog # : H00004009-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human LMX1A peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human LMX1A is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human LMX1A peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 4009
  • GeneBank Accession#:
  • LMX1A
  • Gene Name:
  • LMX1A
  • Gene Alias:
  • LMX-1,LMX1,LMX1.1,MGC87616
  • Gene Description:
  • LIM homeobox transcription factor 1, alpha
  • Gene Summary:
  • Insulin is produced exclusively by the beta cells in the islets of Langerhans in the pancreas. The level and beta-cell specificity of insulin gene expression are regulated by a set of nuclear genes that bind to specific sequences within the promoter of the insulin gene (INS; MIM 176730) and interact with RNA polymerase to activate or repress transcription. LMX1 is a homeodomain protein that binds an A/T-rich sequence in the insulin promoter and stimulates transcription of insulin (German et al., 1994 [PubMed 7698771]).[supplied by OMIM
  • Other Designations:
  • OTTHUMP00000032530,OTTHUMP00000032531,OTTHUMP00000032532
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