LMO2 monoclonal antibody (M05), clone 4D3
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant LMO2.
Immunogen
LMO2 (NP_005565, 16 a.a. ~ 102 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRLFGQDGLCASCDKRIR
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.57 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
LMO2 monoclonal antibody (M05), clone 4D3. Western Blot analysis of LMO2 expression in human spleen.Western Blot (Recombinant protein)
ELISA
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Gene Info — LMO2
Entrez GeneID
4005GeneBank Accession#
NM_005574Protein Accession#
NP_005565Gene Name
LMO2
Gene Alias
RBTN2, RBTNL1, RHOM2, TTG2
Gene Description
LIM domain only 2 (rhombotin-like 1)
Omim ID
180385Gene Ontology
HyperlinkGene Summary
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms
Other Designations
LIM domain only 2|T-cell translocation gene 2|rhombotin 2|rhombotin-like 1
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Interactome
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Disease
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