LMO2 monoclonal antibody (M02), clone 2B3
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant LMO2.
Immunogen
LMO2 (AAH34041, 1 a.a. ~ 158 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MSSAIERKSLDPSEEPVDEVLQIPPSLLTCGGCQQNIGDRYFLKAIDQYWHEDCLSCDLCGCRLGEVGRRLYYKLGRKLCRRDYLRPFGQDGLCASCDKRIRAYEMTMRVKDKVYHLECFKCAACQKHFCVGDRYLLINSDIVCEQDIYEWTKINGMI
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (43.12 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
LMO2 monoclonal antibody (M02), clone 2B3. Western Blot analysis of LMO2 expression in human spleen.Western Blot (Cell lysate)
LMO2 monoclonal antibody (M02), clone 2B3 Western Blot analysis of LMO2 expression in HL-60 ( Cat # L014V1 ).Western Blot (Recombinant protein)
ELISA
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Gene Info — LMO2
Entrez GeneID
4005GeneBank Accession#
BC034041Protein Accession#
AAH34041Gene Name
LMO2
Gene Alias
RBTN2, RBTNL1, RHOM2, TTG2
Gene Description
LIM domain only 2 (rhombotin-like 1)
Omim ID
180385Gene Ontology
HyperlinkGene Summary
LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms
Other Designations
LIM domain only 2|T-cell translocation gene 2|rhombotin 2|rhombotin-like 1
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Interactome
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Disease
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