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LMAN1 (Human) Recombinant Protein (P01)

  • Catalog # : H00003998-P01
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  • Specification
  • Product Description:
  • Human LMAN1 full-length ORF (BAG35721.1, 1 a.a. - 510 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 83.9
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 3998
  • Gene Name:
  • LMAN1
  • Gene Alias:
  • ERGIC-53,ERGIC53,F5F8D,FMFD1,MCFD1,MR60,gp58
  • Gene Description:
  • lectin, mannose-binding, 1
  • Gene Summary:
  • The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished. [provided by RefSeq
  • Other Designations:
  • coagulation factor V-factor VIII combined deficiency,endoplasmic reticulum-golgi intermediate compartment protein 53,intracellular mannose specific lectin
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