LIG3 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant LIG3.
Immunogen
LIG3 (NP_039269, 823 a.a. ~ 922 a.a) partial recombinant protein with GST tag.
Sequence
TKSSPVKVGEKRKAADETLCQTKVLLDIFTGVRLYLPPSTPDFSRLRRYFVAFDGDLVQEFDMTSATHVLGSRDKNPAAQQVSPEWIWACIRKRRLVAPC
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (82)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.11 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — LIG3
Entrez GeneID
3980GeneBank Accession#
NM_013975Protein Accession#
NP_039269Gene Name
LIG3
Gene Alias
LIG2
Gene Description
ligase III, DNA, ATP-dependent
Omim ID
600940Gene Ontology
HyperlinkGene Summary
This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
ligase II, DNA, ATP-dependent|polydeoxyribonucleotide synthase
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Interactome
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Pathway
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Disease
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