LIG1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human LIG1 partial ORF ( NP_000225, 810 a.a. - 919 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
QSLKALVLPSPRPYVRIDGAVIPDHWLDPSAVWEVKCADLSLSPIYPAARGLVDSDKGISLRFPRFIRVREDKQPEQATTSAQVACLYRKQSQIQNQQGEDSGSDPEDTY
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Interspecies Antigen Sequence
Mouse (84%)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LIG1
Entrez GeneID
3978GeneBank Accession#
NM_000234Protein Accession#
NP_000225Gene Name
LIG1
Gene Alias
MGC117397, MGC130025
Gene Description
ligase I, DNA, ATP-dependent
Omim ID
126391Gene Ontology
HyperlinkGene Summary
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq
Other Designations
DNA ligase I
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Interactome
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Pathway
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Disease
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