LIG1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human LIG1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human LIG1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human LIG1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — LIG1
Entrez GeneID
3978GeneBank Accession#
LIG1Gene Name
LIG1
Gene Alias
MGC117397, MGC130025
Gene Description
ligase I, DNA, ATP-dependent
Omim ID
126391Gene Ontology
HyperlinkGene Summary
LIG1 encodes DNA ligase I, with functions in DNA replication and the base excision repair process. Mutations in LIG1 that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents. [provided by RefSeq
Other Designations
DNA ligase I
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Interactome
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Pathway
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Disease
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