LGALS3BP (Human) Recombinant Protein (P01)
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More Files
- More Functions
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Specification
Product Description
Human LGALS3BP full-length ORF ( AAH02403.1, 1 a.a. - 585 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAATPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
90.09
Interspecies Antigen Sequence
Mouse (69)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LGALS3BP
Entrez GeneID
3959GeneBank Accession#
BC002403Protein Accession#
AAH02403.1Gene Name
LGALS3BP
Gene Alias
90K, BTBD17B, MAC-2-BP
Gene Description
lectin, galactoside-binding, soluble, 3 binding protein
Omim ID
600626Gene Ontology
HyperlinkGene Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq
Other Designations
L3 antigen|Mac-2-binding protein|galectin 3 binding protein|serum protein 90K
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Interactome
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Publication Reference
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The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.
Hunt LC, Xu B, Finkelstein D, Fan Y, Carroll PA, Cheng PF, Eisenman RN, Demontis F.
Genes & Development 2015 Dec; 29(23):2475.
Application：Func, Mouse, C2C12 cells.
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The glucose-sensing transcription factor MLX promotes myogenesis via myokine signaling.
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