Immunoprecipitation of LGALS3BP transfected lysate using anti-LGALS3BP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with LGALS3BP purified MaxPab mouse polyclonal antibody (B01P) (H00003959-B01P).
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq
L3 antigen,Mac-2-binding protein,galectin 3 binding protein,serum protein 90K