LGALS3BP MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Western Blot (Tissue lysate)
LGALS3BP MaxPab rabbit polyclonal antibody. Western Blot analysis of LGALS3BP expression in human colon.
Immunoprecipitation
Immunoprecipitation of LGALS3BP transfected lysate using anti-LGALS3BP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with LGALS3BP purified MaxPab mouse polyclonal antibody (B01P) (H00003959-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human LGALS3BP protein.
Immunogen
LGALS3BP (NP_005558.1, 1 a.a. ~ 585 a.a) full-length human protein.
Sequence
MTPPRLFWVWLLVAGTQGVNDGDMRLADGGATNQGRVEIFYRGQWGTVCDNLWDLTDASVVCRALGFENATQALGRAAFGQGSGPIMLDEVQCTGTEASLADCKSLGWLKSNCRHERDAGVVCTNETRSTHTLDLSRELSEALGQIFDSQRGCDLSISVNVQGEDALGFCGHTVILTANLEAQALWKEPGSNVTMSVDAECVPMVRDLLRYFYSRRIDITLSSVKCFHKLASAYGARQLQGYCASLFAILLPQDPSFQMPLDLYAYAVATGDALLEKLCLQFLAWNFEALTQAEAWPSVPTDLLQLLLPRSDLAVPSELALLKAVDTWSWGERASHEEVEGLVEKIRFPMMLPEELFELQFNLSLYWSHEALFQKKTLQALEFHTVPFQLLARYKGLNLTEDTYKPRIYTSPTWSAFVTDSSWSARKSQLVYQSRRGPLVKYSSDYFQAPSDYRYYPYQSFQTPQHPSFLFQDKRVSWSLVYLPTIQSCWNYGFSCSSDELPVLGLTKSGGSDRTIAYENKALMLCEGLFVADVTDFEGWKAAIPSALDTNSSKSTSSFPCPAGHFNGFRTVIRPFYLTNSSGVD
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
LGALS3BP MaxPab rabbit polyclonal antibody. Western Blot analysis of LGALS3BP expression in human colon.Immunoprecipitation
Immunoprecipitation of LGALS3BP transfected lysate using anti-LGALS3BP MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with LGALS3BP purified MaxPab mouse polyclonal antibody (B01P) (H00003959-B01P). -
Gene Info — LGALS3BP
Entrez GeneID
3959GeneBank Accession#
NM_005567.2Protein Accession#
NP_005558.1Gene Name
LGALS3BP
Gene Alias
90K, BTBD17B, MAC-2-BP
Gene Description
lectin, galactoside-binding, soluble, 3 binding protein
Omim ID
600626Gene Ontology
HyperlinkGene Summary
The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1. [provided by RefSeq
Other Designations
L3 antigen|Mac-2-binding protein|galectin 3 binding protein|serum protein 90K
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Interactome
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Publication Reference
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Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.
Doe JA, Wuebbles RD, Allred ET, Rooney JE, Elorza M, Burkin DJ.
J Cell Sci 2011 Jun; 124:2287.
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Transgenic overexpression of the α7 integrin reduces muscle pathology and improves viability in the dy(W) mouse model of merosin-deficient congenital muscular dystrophy type 1A.
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