LCAT monoclonal antibody (M01), clone 4A9
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant LCAT.
Immunogen
LCAT (AAH14781, 98 a.a. ~ 197 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
CWIDNTRVVYNRSSGLVSNAPGVQIRVPGFGKTYSVEYLDSSKLAGYLHTLVQNLVNNGYVRDETVRAAPYDWRLEPGQQEEYYRKLAGLVEEMHAAYGK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (91)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of LCAT expression in transfected 293T cell line by LCAT monoclonal antibody (M01), clone 4A9.
Lane 1: LCAT transfected lysate (Predicted MW: 49.6 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
Immunofluorescence
Immunofluorescence of monoclonal antibody to LCAT on HeLa cell . [antibody concentration 10 ug/ml] -
Gene Info — LCAT
Entrez GeneID
3931GeneBank Accession#
BC014781Protein Accession#
AAH14781Gene Name
LCAT
Gene Alias
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Gene Description
lecithin-cholesterol acyltransferase
Gene Ontology
HyperlinkGene Summary
This gene encodes the extracellular cholesterol esterifying enzyme, lecithin-cholesterol acyltransferase. The esterification of cholesterol is required for cholesterol transport. Mutations in this gene have been found to cause fish-eye disease as well as LCAT deficiency. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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