LBR 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-LBR full-length
Host
Human
Theoretical MW (kDa)
70.7
Interspecies Antigen Sequence
Mouse (79); Rat (79)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-LBR antibody (H00003930-B01) by Western Blots.
SDS-PAGE Gel
LBR transfected lysate.
Western Blot
Lane 1: LBR transfected lysate ( 70.7 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — LBR
Entrez GeneID
3930GeneBank Accession#
NM_002296.2Protein Accession#
-Gene Name
LBR
Gene Alias
DHCR14B, FLJ43126, LMN2R, MGC9041, PHA
Gene Description
lamin B receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq
Other Designations
OTTHUMP00000035631|integral nuclear envelope inner membrane protein
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Interactome
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Disease
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