LAMB3 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human LAMB3 partial ORF ( NP_000219, 1064 a.a. - 1171 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
AEGASEQALSAQEGFERIKQKYAELKDRLGQSSMLGEQGARIQSVKTEAEELFGETMEMMDRMKDMELELLRGSQAIMLRSADLTGLEKRVEQIRDHINGRVLYYATC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.62
Interspecies Antigen Sequence
Mouse (84); Rat (86)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — LAMB3
Entrez GeneID
3914GeneBank Accession#
NM_000228Protein Accession#
NP_000219Gene Name
LAMB3
Gene Alias
BM600-125KDA, FLJ99565, LAM5, LAMNB1
Gene Description
laminin, beta 3
Gene Ontology
HyperlinkGene Summary
The product encoded by this gene is a laminin that belongs to a family of basement membrane proteins. This protein is a beta subunit laminin, which together with an alpha and a gamma subunit, forms laminin-5. Mutations in this gene cause epidermolysis bullosa junctional Herlitz type, and generalized atrophic benign epidermolysis bullosa, diseases that are characterized by blistering of the skin. Multiple alternatively spliced transcript variants that encode the same protein have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000034555|OTTHUMP00000034640|kalinin B1 chain|kalinin-140kDa|laminin B1k chain|laminin S B3 chain|laminin, beta 3 (nicein (125kD), kalinin (140kD), BM600 (125kD))|nicein-125kDa
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Interactome
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Pathway
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Disease
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