LAMA5 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant LAMA5.
Immunogen
LAMA5 (AAH03355, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag.
Sequence
MGVSLRDKKVHWVYQLGEAGPAVLSIDEDIGEQFAAVSLDRTLQFGHMSVTVERQMIQETKGDTVAPGAEGLLNLRPDDFVFYVGGYPSTFTPPPLLRFP
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — LAMA5
Entrez GeneID
3911GeneBank Accession#
BC003355Protein Accession#
AAH03355Gene Name
LAMA5
Gene Alias
KIAA1907
Gene Description
laminin, alpha 5
Omim ID
601033Gene Ontology
HyperlinkGene Summary
Components of the extracellular matrix exert myriad effects on tissues throughout the body. In particular, the laminins, a family of heterotrimeric extracellular glycoproteins, affect tissue development and integrity in such diverse organs as the kidney, lung, skin, and nervous system. It is thought that laminins mediate the attachment, migration, and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Laminins function as heterotrimeric complexes of alpha, beta, and gamma chains, with each chain type representing a different subfamily of proteins. The protein encoded by this gene belongs to the alpha subfamily of laminin chains and is a major component of basement membranes. Two transcript variants encoding different isoforms have been found for this gene, but the full-length nature of one of them has not been determined. [provided by RefSeq
Other Designations
laminin alpha 5|laminin alpha-5 chain
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Interactome
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Pathway
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Disease
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Publication Reference
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Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration.
Kariya Y, Sato H, Katou N, Kariya Y, Miyazaki K.
PLoS One 2012 May; 7(5):e35546.
Application:WB, Human, HEK 293 cells.
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Polymerized laminin-332 matrix supports rapid and tight adhesion of keratinocytes, suppressing cell migration.
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