KRTHB1 MaxPab mouse polyclonal antibody (B01P)
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More Files
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human KRTHB1 protein.
Immunogen
KRTHB1 (AAH21241.1, 1 a.a. ~ 202 a.a) full-length human protein.
Sequence
MKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGIGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAPCGQLNTTCGGGSCGVGSCGISSLGVGSCGSSCRKC
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of KRT81 expression in transfected 293T cell line (H00003887-T01) by KRT81 MaxPab polyclonal antibody.
Lane 1: KRTHB1 transfected lysate(22.22 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — KRT81
Entrez GeneID
3887GeneBank Accession#
BC021241.2Protein Accession#
AAH21241.1Gene Name
KRT81
Gene Alias
HB1, Hb-1, KRTHB1, MLN137, ghHkb1, hHAKB2-1
Gene Description
keratin 81
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. [provided by RefSeq
Other Designations
hard keratin, type II, 1|keratin, hair, basic, 1
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