TNPO1 (Human) Recombinant Protein (Q01)
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Specification
Product Description
Human TNPO1 partial ORF ( NP_002261, 25 a.a. - 141 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PDTTIQRTVQQKLEQLNQYPDFNNYLIFVLTKLKSEDEPTRSLSGLILKNNVKAHFQNFPNGVTDFIKSECLNNIGDSSPLIRATVGILITTIASKGELQNWPDLLPKLCSLLDSED
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
38.61
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TNPO1
Entrez GeneID
3842GeneBank Accession#
NM_002270Protein Accession#
NP_002261Gene Name
TNPO1
Gene Alias
IPO2, KPNB2, MIP, MIP1, TRN
Gene Description
transportin 1
Omim ID
602901Gene Ontology
HyperlinkGene Summary
This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. [provided by RefSeq
Other Designations
M9 region interaction protein|OTTHUMP00000126960|importin 2|importin beta 2|karyopherin (importin) beta 2
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