TNPO1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human TNPO1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human TNPO1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human TNPO1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — TNPO1
Entrez GeneID
3842GeneBank Accession#
TNPO1Gene Name
TNPO1
Gene Alias
IPO2, KPNB2, MIP, MIP1, TRN
Gene Description
transportin 1
Omim ID
602901Gene Ontology
HyperlinkGene Summary
This gene encodes the beta subunit of the karyopherin receptor complex which interacts with nuclear localization signals to target nuclear proteins to the nucleus. The karyopherin receptor complex is a heterodimer of an alpha subunit which recognizes the nuclear localization signal and a beta subunit which docks the complex at nucleoporins. Alternate splicing of this gene results in two transcript variants encoding different proteins. [provided by RefSeq
Other Designations
M9 region interaction protein|OTTHUMP00000126960|importin 2|importin beta 2|karyopherin (importin) beta 2
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Interactome
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