KLRC1 purified MaxPab rabbit polyclonal antibody (D01P)
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human KLRC1 protein.
Immunogen
KLRC1 (NP_002250.1, 1 a.a. ~ 233 a.a) full-length human protein.
Sequence
MDNQGVIYSDLNLPPNPKRQQRKPKGNKSSILATEQEITYAELNLQKASQDFQGNDKTYHCKDLPSAPEKLIVGILGIICLILMASVVTIVVIPSTLIQRHNNSSLNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLSIISPSSWIGVFRNSSHHPWVTMNGLAFKHEIKDSDNAELNCAVLQVNRLKSAQCGSSIIYHCKHKL
Host
Rabbit
Reactivity
Human, Mouse
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
KLRC1 MaxPab rabbit polyclonal antibody. Western Blot analysis of KLRC1 expression in human spleen.Western Blot (Tissue lysate)
KLRC1 MaxPab rabbit polyclonal antibody. Western Blot analysis of KLRC1 expression in mouse testis.Western Blot (Transfected lysate)
Western Blot analysis of KLRC1 expression in transfected 293T cell line (H00003821-T02) by KLRC1 MaxPab polyclonal antibody.
Lane 1: KLRC1 transfected lysate(26.30 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — KLRC1
Entrez GeneID
3821GeneBank Accession#
NM_002259Protein Accession#
NP_002250.1Gene Name
KLRC1
Gene Alias
CD159A, MGC13374, MGC59791, NKG2, NKG2A
Gene Description
killer cell lectin-like receptor subfamily C, member 1
Omim ID
161555Gene Ontology
HyperlinkGene Summary
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells. The genes of NKG2 family members form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq
Other Designations
C-lectin type II protein|NK cell receptor A|NKG2-1/B activating NK receptor|NKG2-A/B type II integral membrane protein|natural killer cell lectin|natural killer group protein 2
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Interactomes
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Pathways
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Diseases
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