KISS1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human KISS1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MNSLVSWQLLLFLCATHFGEPLEKVASVGNSRPTGQQLESLGLLAPGEQSLPCTERKPAATARLSRRGTSLSPPPESSGSPQQPGLSAPHSRQIPAPQGAVLVQREKDLPNYNWNSFGLRFGKREAAPGNHGRSAGRG
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — KISS1
Entrez GeneID
3814GeneBank Accession#
NM_002256.3Protein Accession#
NP_002247.3Gene Name
KISS1
Gene Alias
KiSS-1, METASTIN, MGC39258
Gene Description
KiSS-1 metastasis-suppressor
Omim ID
603286Gene Ontology
HyperlinkGene Summary
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq
Other Designations
OTTHUMP00000034312|kisspeptin|malignant melanoma metastasis-suppressor
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Interactome
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Disease
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