KISS1 (Human) Matched Antibody Pair
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Specification
Product Description
This antibody pair set comes with a matched antibody pair to detect and quantify the protein level of human KISS1.
Reactivity
Human
Quality Control Testing
Standard curve using recombinant protein ( H00003814-P01 ) as an analyte.
Sandwich ELISA detection sensitivity ranging from 10 ng/ml to 100 ng/ml.
Supplied Product
Antibody pair set content:
1. Capture antibody: mouse monoclonal anti-KISS1, IgG2a Kappa (100 ug)
2. Detection antibody: biotinylated mouse monoclonal anti-KISS1, IgG2a Kappa (50 ug)
*Reagents are sufficient for at least 3-5 x 96 well plates using recommended protocols.Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
ELISA Pair (Recombinant protein)
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Gene Info — KISS1
Entrez GeneID
3814Gene Name
KISS1
Gene Alias
KiSS-1, METASTIN, MGC39258
Gene Description
KiSS-1 metastasis-suppressor
Omim ID
603286Gene Ontology
HyperlinkGene Summary
This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may function to inhibit chemotaxis and invasion, attenuating metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq
Other Designations
OTTHUMP00000034312|kisspeptin|malignant melanoma metastasis-suppressor
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Interactome
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Disease
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