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KIR2DL1 293T Cell Transient Overexpression Lysate(Denatured)

  • Catalog # : H00003802-T02
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  • Specification
  • Transfected Cell Line:
  • 293T
  • Plasmid:
  • pCMV-KIR2DL1 full-length
  • Host:
  • Human
  • Theoretical MW (kDa):
  • 41.4
  • Quality Control Testing:
  • Transient overexpression cell lysate was tested with Anti-KIR2DL1 antibody (H00003802-D01P) by Western Blots.
    SDS-PAGE Gel
    QC Testing of H00003802-T02
    KIR2DL1 transfected lysate.
    Western Blot
    QC Testing of H00003802-T02
    Lane 1: KIR2DL1 transfected lysate ( 41.40 KDa)
    Lane 2: Non-transfected lysate.
  • Storage Buffer:
  • 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 3802
  • Gene Name:
  • KIR2DL1
  • Gene Alias:
  • CD158A,KIR-K64,KIR221,NKAT,NKAT1,p58.1
  • Gene Description:
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
  • Gene Summary:
  • Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq
  • Other Designations:
  • killer inhibitory receptor 2-2-1,natural killer-associated transcript 1,p58 NK cell inhibitory receptor NKR-K6,p58 killer cell inhibitory receptor KIR-K64,p58 natural killer cell receptor
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