KCNQ2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
KCNQ2 transfected lysate.
Western Blot
Lane 1: KCNQ2 transfected lysate ( 44.3 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-KCNQ2 full-length
Host
Human
Theoretical MW (kDa)
44.3
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-KCNQ2 antibody (H00003785-B01) by Western Blots.
SDS-PAGE Gel
KCNQ2 transfected lysate.
Western Blot
Lane 1: KCNQ2 transfected lysate ( 44.3 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — KCNQ2
Entrez GeneID
3785GeneBank Accession#
NM_172109.1Protein Accession#
-Gene Name
KCNQ2
Gene Alias
BFNC, EBN, EBN1, ENB1, HNSPC, KCNA11, KV7.2, KVEBN1
Gene Description
potassium voltage-gated channel, KQT-like subfamily, member 2
Gene Ontology
HyperlinkGene Summary
The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. [provided by RefSeq
Other Designations
neuroblastoma-specific potassium channel protein|potassium voltage-gated channel KQT-like protein 2
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Interactome
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Disease
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