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Last updated: 2016/12/4

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KCNN4 rabbit monoclonal antibody

  • Catalog # : H00003783-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human KCNN4 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human KCNN4 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human KCNN4 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3783
  • GeneBank Accession#:
  • KCNN4
  • Gene Name:
  • KCNN4
  • Gene Alias:
  • IK1,IKCA1,KCA4,KCa3.1,SK4,hIKCa1,hKCa4,hSK4
  • Gene Description:
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
  • Gene Summary:
  • The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq
  • Other Designations:
  • intermediate conductance calcium-activated potassium channel protein 1,putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel
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