KCNN4 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Tissue lysate)
KCNN4 MaxPab polyclonal antibody. Western Blot analysis of KCNN4 expression in human kidney.
Western Blot (Transfected lysate)
Western Blot analysis of KCNN4 expression in transfected 293T cell line (H00003783-T01) by KCNN4 MaxPab polyclonal antibody.
Lane 1: KCNN4 transfected lysate(47.7 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human KCNN4 protein.
Immunogen
KCNN4 (NP_002241.1, 1 a.a. ~ 427 a.a) full-length human protein.
Sequence
MGGDLVLGLGALRRRKRLLEQEKSLAGWALVLAGTGIGLMVLHAEMLWFGGCSWALYLFLVKCTISISTFLLLCLIVAFHAKEVQLFMTDNGLRDWRVALTGRQAAQIVLELVVCGLHPAPVRGPPCVQDLGAPLTSPQPWPGFLGQGEALLSLAMLLRLYLVPRAVLLRSGVLLNASYRSIGALNQVRFRHWFVAKLYMNTHPGRLLLGLTLGLWLTTAWVLSVAERQAVNATGHLSDTLWLIPITFLTIGYGDVVPGTMWGKIVCLCTGVMGVCCTALLVAVVARKLEFNKAEKHVHNFMMDIQYTKEMKESAARVLQEAWMFYKHTRRKESHAARRHQRKLLAAINAFRQVRLKHRKLREQVNSMVDISKMHMILYDLQQNLSSSHRALEKQIDTLAGKLDALTELLSTALGPRQLPEPSQQSK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Rat (86)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
KCNN4 MaxPab polyclonal antibody. Western Blot analysis of KCNN4 expression in human kidney.Western Blot (Transfected lysate)
Western Blot analysis of KCNN4 expression in transfected 293T cell line (H00003783-T01) by KCNN4 MaxPab polyclonal antibody.
Lane 1: KCNN4 transfected lysate(47.7 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — KCNN4
Entrez GeneID
3783GeneBank Accession#
NM_002250.2Protein Accession#
NP_002241.1Gene Name
KCNN4
Gene Alias
IK1, IKCA1, KCA4, KCa3.1, SK4, hIKCa1, hKCa4, hSK4
Gene Description
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
Omim ID
602754Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is part of a potentially heterotetrameric voltage-independent potassium channel that is activated by intracellular calcium. Activation is followed by membrane hyperpolarization, which promotes calcium influx. The encoded protein may be part of the predominant calcium-activated potassium channel in T-lymphocytes. This gene is similar to other KCNN family potassium channel genes, but it differs enough to possibly be considered as part of a new subfamily. [provided by RefSeq
Other Designations
intermediate conductance calcium-activated potassium channel protein 1|putative erythrocyte intermediate conductance calcium-activated potassium Gardos channel
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Interactome
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Disease
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Publication Reference
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Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions?
Wong PS, Roberts RE, Randall MD.
British Journal of Pharmacology 2014 Jun; 171(11):2751.
Application：WB-Ti, Pig, Porcine coronary arteries, Kidney.
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Sex differences in endothelial function in porcine coronary arteries: a role for H2O2 and gap junctions?
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