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Last updated: 2016/12/4
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KCNN3 polyclonal antibody (A01)

  • Catalog # : H00003782-A01
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant KCNN3.
  • Immunogen:
  • KCNN3 (NP_740752, 301 a.a. ~ 410 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • QAIHQLRSVKMEQRKLSDQANTLVDLSKMQNVMYDLITELNDRSEDLEKQIGSLESKLEHLTASFNSLPLLIADTLRQQQQQLLSAIIEARGVSVAVGTTHTPISDSPIG
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00003782-A01
    Western Blot detection against Immunogen (38.21 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • KCNN3 polyclonal antibody (A01), Lot # 050921JC01 Western Blot analysis of KCNN3 expression in Y-79 ( Cat # L042V1 ).
  • PDF DownloadProtocol Download
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3782
  • Gene Name:
  • KCNN3
  • Gene Alias:
  • KCa2.3,SK3,SKCA3,hSK3
  • Gene Description:
  • potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
  • Gene Summary:
  • Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding two different isoforms have been found for this gene. One of the variants lacks the CAG repeat regions. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000035369,OTTHUMP00000042458,OTTHUMP00000042459,small conductance calcium-activated potassium channel protein 3
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