KCNJ6 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human KCNJ6 full-length ORF ( NP_002231.1, 1 a.a. - 423 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MAKLTESMTNVLEGDSMDQDVESPVAIHQPKLPKQARDDLPRHISRDRTKRKIQRYVRKDGKCNVHHGNVRETYRYLTDIFTTLVDLKWRFNLLIFVMVYTVTWLFFGMIWWLIAYIRGDMDHIEDPSWTPCVTNLNGFVSAFLFSIETETTIGYGYRVITDKCPEGIILLLIQSVLGSIVNAFMVGCMFVKISQPKKRAETLVFSTHAVISMRDGKLCLMFRVGDLRNSHIVEASIRAKLIKSKQTSEGEFIPLNQTDINVGYYTGDDRLFLVSPLIISHEINQQSPFWEISKAQLPKEELEIVVILEGMVEATGMTCQARSSYITSEILWGYRFTPVLTLEDGFYEVDYNSFHETYETSTPSLSAKELAELASRAELPLSWSVSSKLNQHAELETEEEEKNLEEQTERNGDVANLENESKV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
74.9
Interspecies Antigen Sequence
Mouse (99); Rat (99)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KCNJ6
Entrez GeneID
3763GeneBank Accession#
NM_002240.2Protein Accession#
NP_002231.1Gene Name
KCNJ6
Gene Alias
BIR1, GIRK2, KATP2, KCNJ7, KIR3.2, MGC126596, hiGIRK2
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 6
Omim ID
600877Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and may be involved in the regulation of insulin secretion by glucose. It associates with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq
Other Designations
G protein-activated inward rectifier potassium channel 2|OTTHUMP00000109101|inward rectifier potassium channel KIR3.2|potassium inwardly-rectifying channel J6
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Interactome
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Disease
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