KCNJ5 monoclonal antibody (M01), clone 8D2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KCNJ5.
Immunogen
KCNJ5 (NP_000881.3, 321 a.a. ~ 419 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
SYMDTEVLWGHRFTPVLTLEKGFYEVDYNTFHDTYETNTPSCCAKELAEMKREGRLLQYLPSPPLLGGCAEAGLDAEAEQNEEDEPKGLGGSREARGSV
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (87); Rat (85)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.63 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
KCNJ5 monoclonal antibody (M01), clone 8D2. Western Blot analysis of KCNJ5 expression in K-562.Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KCNJ5 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — KCNJ5
Entrez GeneID
3762GeneBank Accession#
NM_000890Protein Accession#
NP_000881.3Gene Name
KCNJ5
Gene Alias
CIR, GIRK4, KATP1, KIR3.4
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 5
Omim ID
600734Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. It may associate with two other G-protein-activated potassium channels to form a heteromultimeric pore-forming complex. [provided by RefSeq
Other Designations
G protein-activated inward rectifier potassium channel 4 (GIRK4) (Potassium channel, inwardly rectifying, subfamily J, member 5) (Inward rectifier K+ channel Kir3.4) (Heart KATP channel) (KATP-1) (Cardiac inward rectifier) (CIR)...|cardiac ATP-sensitive p
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Interactome
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Disease
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