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Last updated: 2017/9/24

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KCNJ4 rabbit monoclonal antibody

  • Catalog # : H00003761-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human KCNJ4 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human KCNJ4 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human KCNJ4 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3761
  • GeneBank Accession#:
  • KCNJ4
  • Gene Name:
  • KCNJ4
  • Gene Alias:
  • HIR,HIRK2,HRK1,IRK3,Kir2.3,MGC142066,MGC142068
  • Gene Description:
  • potassium inwardly-rectifying channel, subfamily J, member 4
  • Gene Summary:
  • Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000028922,hippocampal inward rectifier potassium channel,inward rectifier K+ channel Kir2.3,potassium inwardly-rectifying channel J4
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