KCNJ2 (Human) Recombinant Protein (Q01)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Human KCNJ2 partial ORF ( NP_000882, 328 a.a. - 427 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
PVLFEEKHYYKVDYSRFHKTYEVPNTPLCSARDLAEKKYILSNANSFCYENEVALTSKEEDDSENGVPESTSTDTPPDIDLHNQASVPLEPRPLRRESEI
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
36.74
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
-
Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
-
Gene Info — KCNJ2
Entrez GeneID
3759GeneBank Accession#
NM_000891Protein Accession#
NP_000882Gene Name
KCNJ2
Gene Alias
HHBIRK1, HHIRK1, IRK1, KIR2.1, LQT7, SQT3
Gene Description
potassium inwardly-rectifying channel, subfamily J, member 2
Gene Ontology
HyperlinkGene Summary
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq
Other Designations
cardiac inward rectifier potassium channel|inward rectifier K+ channel KIR2.1|inward rectifier potassium channel 2|potassium inwardly-rectifying channel J2
-
Interactome
-
Disease
-
Publication Reference
-
Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia.
Yuko Maejima, Shoichiro Horita, Shoko Yokota, Megumi Yamachi, Masaru Shimizu, Tomoyuki Ono, Zhiquian Yu, Hiroaki Tomita, Kenju Shimomura.
Molecular and Cellular Neurosciences 2022 May; 120:103734.
Application：WB, Human, N/A.
-
Surface translocation of Kir2.1 channel induces IL-1β secretion in microglia.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com