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Last updated: 2017/6/25

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KCNJ2 rabbit monoclonal antibody

  • Catalog # : H00003759-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human KCNJ2 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human KCNJ2 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human KCNJ2 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3759
  • GeneBank Accession#:
  • KCNJ2
  • Gene Name:
  • KCNJ2
  • Gene Alias:
  • HHBIRK1,HHIRK1,IRK1,KIR2.1,LQT7,SQT3
  • Gene Description:
  • potassium inwardly-rectifying channel, subfamily J, member 2
  • Gene Summary:
  • Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq
  • Other Designations:
  • cardiac inward rectifier potassium channel,inward rectifier K+ channel KIR2.1,inward rectifier potassium channel 2,potassium inwardly-rectifying channel J2
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