Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

KCNH1

Gene Alias

EAG, EAG1, Kv10.1, MGC142269, h-eag

Gene Description

potassium voltage-gated channel, subfamily H (eag-related), member 1

Omim ID

Gene Ontology

Gene Summary

Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily H. This member is a pore-forming (alpha) subunit of a voltage-gated non-inactivating delayed rectifier potassium channel. It is activated at the onset of myoblast differentiation. The gene is highly expressed in brain and in myoblasts. Overexpression of the gene may confer a growth advantage to cancer cells and favor tumor cell proliferation. Alternative splicing of this gene results in two transcript variants encoding distinct isoforms. [provided by RefSeq

Other Designations

OTTHUMP00000034451|OTTHUMP00000034569|ether-a-go-go potassium channel 1|ether-a-go-go, Drosophila, homolog of|potassium channel, voltage-gated, subfamily H, member 1|potassium voltage-gated channel, subfamily H, member 1