KCNA1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
KCNA1 transfected lysate.
Western Blot
Lane 1: KCNA1 transfected lysate ( 54.56 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-KCNA1 full-length
Host
Human
Theoretical MW (kDa)
54.56
Interspecies Antigen Sequence
Mouse (98); Rat (98)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-KCNA1 antibody (H00003736-B01) by Western Blots.
SDS-PAGE Gel
KCNA1 transfected lysate.
Western Blot
Lane 1: KCNA1 transfected lysate ( 54.56 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — KCNA1
Entrez GeneID
3736GeneBank Accession#
NM_000217.1Protein Accession#
NP_000208.2Gene Name
KCNA1
Gene Alias
AEMK, EA1, HBK1, HUK1, KV1.1, MBK1, MGC126782, MGC138385, MK1, RBK1
Gene Description
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
Gene Ontology
HyperlinkGene Summary
This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq
Other Designations
potassium voltage-gated channel subfamily A member 1|voltage-gated potassium channel subunit Kv1.1
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Interactome
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Disease
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