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KCNA1 Pre-design Chimera RNAi

  • Catalog # : H00003736-R01
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Homo sapiens potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia) (KCNA1), mRNA.
  • Reactivity:
  • Human
  • Supplied Product:
  • DEPC water
  • Target Refseq:
  • NM_000217
  • Storage Instruction:
  • Store at -20°C, do not exceed 4 - 5 freeze-thaw cycles to ensure product integrity.
  • Note:
  • Position of the Chimera RNAi.

  • Publication Reference
  • Applications
  • RNAi Knockdown
  • Application Image
  • RNAi Knockdown
  • Gene Information
  • Entrez GeneID:
  • 3736
  • Gene Name:
  • KCNA1
  • Gene Alias:
  • AEMK,EA1,HBK1,HUK1,KV1.1,MBK1,MGC126782,MGC138385,MK1,RBK1
  • Gene Description:
  • potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
  • Gene Summary:
  • This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq
  • Other Designations:
  • potassium voltage-gated channel subfamily A member 1,voltage-gated potassium channel subunit Kv1.1
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