Products

Sandwich ELISA (Recombinant protein)

Detection limit for recombinant GST tagged CD82 is approximately 0.3ng/ml as a capture antibody.

ELISA

In situ Proximity Ligation Assay (Cell)

Proximity Ligation Analysis of protein-protein interactions between CD19 and CD82. HeLa cells were stained with anti-CD19 rabbit purified polyclonal 1:1200 and anti-CD82 mouse monoclonal antibody 1:50. Each red dot represents the detection of protein-protein interaction complex, and nuclei were counterstained with DAPI (blue).

Entrez GeneID

3732

GeneBank Accession#

BC000726

Protein Accession#

AAH00726

Gene Name

CD82

Gene Alias

4F9, C33, GR15, IA4, KAI1, R2, SAR2, ST6, TSPAN27

Gene Description

CD82 molecule

Omim ID

176807 600623

Gene Ontology

Hyperlink

Gene Summary

This metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression of this gene has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq

Other Designations

C33 antigen|CD82 antigen|R2 leukocyte antigen|inducible membrane protein R2|kangai 1 (suppression of tumorigenicity 6, prostate; CD82 antigen (R2 leukocyte antigen, antigen detected by monoclonal and antibody IA4))|suppression of tumorigenicity 6|suppress