KAL1 (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human KAL1 partial ORF ( NP_000207, 548 a.a. - 657 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
LAKPENLSASFIVQDVNITGHFSWKMAKANLYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGEGPATIKTFRTPELPP
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
37.84
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — KAL1
Entrez GeneID
3730GeneBank Accession#
NM_000216Protein Accession#
NP_000207Gene Name
KAL1
Gene Alias
ADMLX, HHA, KAL, KALIG-1, KMS
Gene Description
Kallmann syndrome 1 sequence
Omim ID
308700Gene Ontology
HyperlinkGene Summary
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq
Other Designations
Kallmann syndrome 1 protein|Kallmann syndrome interval gene 1|Kallmann syndrome-1 sequence (anosmin-1)|OTTHUMP00000022873|adhesion molecule-like X-linked|anosmin-1
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Interactome
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Disease
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Publication Reference
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Keratinocyte-derived anosmin-1, an extracellular glycoprotein encoded by the X-linked Kallmann syndrome gene, is involved in modulation of epidermal nerve density in atopic dermatitis.
Tengara S, Tominaga M, Kamo A, Taneda K, Negi O, Ogawa H, Takamori K.
Journal of Dermatological Science 2010 Apr; 58(1):64.
Application:WB, Hamster, CHO cells.
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Keratinocyte-derived anosmin-1, an extracellular glycoprotein encoded by the X-linked Kallmann syndrome gene, is involved in modulation of epidermal nerve density in atopic dermatitis.
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