KAL1 monoclonal antibody (M01), clone 2E8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant KAL1.
Immunogen
KAL1 (NP_000207, 548 a.a. ~ 657 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
LAKPENLSASFIVQDVNITGHFSWKMAKANLYQPMTGFQVTWAEVTTESRQNSLPNSIISQSQILPSDHYVLTVPNLRPSTLYRLEVQVLTPGGEGPATIKTFRTPELPP
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.84 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged KAL1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — KAL1
Entrez GeneID
3730GeneBank Accession#
NM_000216Protein Accession#
NP_000207Gene Name
KAL1
Gene Alias
ADMLX, HHA, KAL, KALIG-1, KMS
Gene Description
Kallmann syndrome 1 sequence
Omim ID
308700Gene Ontology
HyperlinkGene Summary
Mutations in this gene cause the X-linked Kallmann syndrome. The encoded protein is similar in sequence to proteins known to function in neural cell adhesion and axonal migration. In addition, this cell surface protein is N-glycosylated and may have anti-protease activity. [provided by RefSeq
Other Designations
Kallmann syndrome 1 protein|Kallmann syndrome interval gene 1|Kallmann syndrome-1 sequence (anosmin-1)|OTTHUMP00000022873|adhesion molecule-like X-linked|anosmin-1
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Interactome
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Disease
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Publication Reference
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Keratinocyte-derived anosmin-1, an extracellular glycoprotein encoded by the X-linked Kallmann syndrome gene, is involved in modulation of epidermal nerve density in atopic dermatitis.
Tengara S, Tominaga M, Kamo A, Taneda K, Negi O, Ogawa H, Takamori K.
Journal of Dermatological Science 2010 Apr; 58(1):64.
Application:WB, Hamster, CHO cells.
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Keratinocyte-derived anosmin-1, an extracellular glycoprotein encoded by the X-linked Kallmann syndrome gene, is involved in modulation of epidermal nerve density in atopic dermatitis.
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