JUP 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-JUP full-length
Host
Human
Theoretical MW (kDa)
81.7
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-JUP antibody (H00003728-D01P) by Western Blots.
SDS-PAGE Gel
JUP transfected lysate.
Western Blot
Lane 1: JUP transfected lysate ( 81.70 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — JUP
Entrez GeneID
3728GeneBank Accession#
NM_002230.1Protein Accession#
NP_002221.1Gene Name
JUP
Gene Alias
ARVD12, CTNNG, DP3, DPIII, PDGB, PKGB
Gene Description
junction plakoglobin
Gene Ontology
HyperlinkGene Summary
This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions. This protein forms distinct complexes with cadherins and desmosomal cadherins and is a member of the catenin family since it contains a distinct repeating amino acid motif called the armadillo repeat. Mutation in this gene has been associated with Naxos disease. Alternative splicing occurs in this gene; however, not all transcripts have been fully described. [provided by RefSeq
Other Designations
OTTHUMP00000164735|catenin (cadherin-associated protein), gamma (80kD)|catenin (cadherin-associated protein), gamma 80kDa|gamma-catenin
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Interactome
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Pathway
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Disease
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