JAG2 monoclonal antibody (M09), clone 1C5
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant JAG2.
Immunogen
JAG2 (NP_002217, 121 a.a. ~ 210 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
AGGDQDPGLVVIPFQFAWPRSFTLIVEAWDWDNDTTPNEELLIERVSHAGMINPEDRWKSLHFSGHVAHLELQIRVRCDENYYSAPCNKF
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (35.64 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
JAG2 monoclonal antibody (M09), clone 1C5 Western Blot analysis of JAG2 expression in Jurkat ( Cat # L017V1 ).Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged JAG2 is approximately 0.03ng/ml as a capture antibody.ELISA
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Gene Info — JAG2
Entrez GeneID
3714GeneBank Accession#
NM_002226Protein Accession#
NP_002217Gene Name
JAG2
Gene Alias
HJ2, SER2
Gene Description
jagged 2
Omim ID
602570Gene Ontology
HyperlinkGene Summary
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
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