ITK 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ITK full-length
Host
Human
Theoretical MW (kDa)
68.31
Interspecies Antigen Sequence
Mouse (93); Rat (94)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ITK antibody (H00003702-B01) by Western Blots.
SDS-PAGE Gel
ITK transfected lysate.
Western Blot
Lane 1: ITK transfected lysate ( 68.31 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ITK
Entrez GeneID
3702GeneBank Accession#
NM_005546.3Protein Accession#
AAI09078.1Gene Name
ITK
Gene Alias
EMT, LYK, MGC126257, MGC126258, PSCTK2
Gene Description
IL2-inducible T-cell kinase
Omim ID
186973Gene Ontology
HyperlinkGene Summary
This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation. [provided by RefSeq
Other Designations
homolog of mouse T-cell itk/tsk|tyrosine-protein kinase ITK/TSK|tyrosine-protein kinase LYK
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Interactome
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Disease
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