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EIF6 rabbit monoclonal antibody

  • Catalog # : H00003692-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human EIF6 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human EIF6 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human EIF6 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • Application Image
  • Western Blot (Transfected lysate)
  • Gene Information
  • Entrez GeneID:
  • 3692
  • GeneBank Accession#:
  • EIF6
  • Gene Name:
  • EIF6
  • Gene Alias:
  • 2,CAB,EIF3A,ITGB4BP,b,b(2)gcn,gcn,p27BBP
  • Gene Description:
  • eukaryotic translation initiation factor 6
  • Gene Summary:
  • Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • B4 integrin interactor,OTTHUMP00000030734,OTTHUMP00000061360,OTTHUMP00000061361,eukaryotic translation initiation factor 3A,integrin beta 4 binding protein,p27 beta-4 integrin-binding protein
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